Experimental Uraemia with Associated Plasma Amino Acid Abnormalities but without Retarded Food Intake and Weight Gain
作者:
D.J. Haines,
C.H.J. Swan,
J.R.B. Green,
J.F. Woodley,
期刊:
Nephron
(Karger Available online 1989)
卷期:
Volume 53,
issue 3
页码: 233-237
ISSN:1660-8151
年代: 1989
DOI:10.1159/000185750
出版商: S. Karger AG
关键词: Kidney failure;Uraemia;Amino acids;Body weight;Food
数据来源: Karger
摘要:
A rat model of moderate uraemia is described in which uraemic animals attain normal food intake and weight gain. Despite the low levels of the induced uraemia, which has been well defined, changes in plasma amino acid concentrations associated with experimental uraemia still occur. It appears from this study that a reduction in food intake is not a major factor in the aetiology of the plasma amino acid changes seen in uraemia and that the model may prove useful in future studies of experimental chronic renal failure.
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