Summary:The effects of both task-induced activation and gender on electroencephalographic (EEG) indices of cortical activity were examined using a verbal and a spatial task previously found to produce differential hemispheric activation patterns across genders with regional cerebral blood flow (rCBF) measures (e.g., Gur et al., 1982). EEG was recorded from 16 men and 14 women during baseline (resting with eyes open) and during each task condition. The regional distributions of two EEG indices, beta (13–32 Hz) and alpha (8–13 Hz), were examined. The results indicated that both measures were sensitive to hemispheric task activation effects. In addition, females had higher baseline levels of activity and greater hemispheric asymmetry of activation for the verbal and spatial tasks. These findings are similar to previous rCBF findings and suggest that EEG and rCBF measures reflect comparable aspects of cortical activity.