Nonsuppressible Insulin-Like Activity in Rat Organs as Detected by Fluorescent Antibody and Radioimmunoassay Techniques
作者:
Rosemaria Liske,
Kurt Reber,
期刊:
Hormone Research in Paediatrics
(Karger Available online 1976)
卷期:
Volume 7,
issue 4-5
页码: 214-217
ISSN:1663-2818
年代: 1976
DOI:10.1159/000178731
出版商: S. Karger AG
关键词: NSILA-S;Fluorescent antibody;Radioimmunoassay;Tissue distribution;Organ concentration;Rats
数据来源: Karger
摘要:
NSILA-S was localized by immunofluorescent antibody staining in the exocrine part of the pancreas and the submaxillary salivary gland of the rat, where part of the cells give positive reactions. To a lesser degree it was demonstrated in the kidney, where some – probably the actually functioning – nephrons give positive staining reactions within their tubular cells. Radioimmunoassayable NSILA-S was found in extracts of the pancreas (120–550 ng/g), of the submaxillary salivary gland (220–330 ng/g) and of the kidney (45 ng/g), whereas liver (and some other organs) contain practically no
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