The human basophil degranulation testasaninvitromethod for the diagnosis of allergies
作者:
J. BENVENISTE,
期刊:
Clinical&Experimental Allergy
(WILEY Available online 1981)
卷期:
Volume 11,
issue 1
页码: 1-11
ISSN:0954-7894
年代: 1981
DOI:10.1111/j.1365-2222.1981.tb01559.x
出版商: Blackwell Publishing Ltd
数据来源: WILEY
摘要:
SummaryWe have designed a human basophil degranulation test based on a one‐step method of basophil staining after exposure to a specific allergen. This very simple test is now commercially available as a ready‐to‐use kit. It explores the allergic sensitivity at the cellular level, probably through IgE‐dependent sensilization of the basophil. It positively correlates with histamine release and radioallergosorbent test (RAST). It detects sensitivity to common allergens and to chemical and food products as well. In its present state, the test provides a simple, inexpensive specific means forin vitrodiagnosis of allergic diseases, Recently, it has been further developed to be performed on the automatic Hemalog D Technicon
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