Use of the FAB Crriteria for the Diagnosis of Acute Erythroleukaemia (AEL)
作者:
R. K. Woodruff,
I. H. Buncei,
S. Jphnsons,
A. M. Paxton,
J. S. Malpas,
期刊:
Australian and New Zealand Journal of Medicine
(WILEY Available online 1981)
卷期:
Volume 11,
issue 1
页码: 1-12
ISSN:0004-8291
年代: 1981
DOI:10.1111/j.1445-5994.1981.tb03728.x
出版商: Blackwell Publishing Ltd
关键词: Acute erythroleukaemia
数据来源: WILEY
摘要:
Abstract:Use of the FA6 criteria for the diagnosis of acute erythroleukaemia (AEL). R. K. Woodruff, I. H. Bunce, S. Johnson, A. in. Paxton and J. S. malpas,Aust. N.Z. J. med., 1981, 11, pp. 1–7.The criteria proposed by the French‐American‐British (FAB) Group for the diagnosis of acute erythroleukaemia (AEL), including the requirement for ≥ 30% marrow myeloblasts, were used in a review of patients with erythroleukaemia. Ten patients with AEL were identified, and a further twelve patients with marrows suggestive of AEL but having<30% myeloblasts were classified as having refractory anemia with excess of blasts (RAEB). The AEL patients had a poor prognosis, poor response to chemotherapy, and none showed evolution to myeloblastic or monoblastic leukaemia. In contrast, the patients with RAEB appeared to survive longer, respond better to chemotherapy, and several evolved into typical myelogenous leukaemiaThe FAB criteria subdivides patients with erythroleukaemia into groups with apparent clinic pathological and prognostic differences. Further studies using these or equally strict criteria are
点击下载:
PDF
(725KB)
返 回