Red Cell Preservation in Protein‐Poor Media: III. Protection Against in vitro Hemolysis
作者:
Claes F. Högman,
Kenneth Hedlund,
Ylva Sahlestrom,
期刊:
Vox Sanguinis
(WILEY Available online 1981)
卷期:
Volume 41,
issue 5‐6
页码: 274-281
ISSN:0042-9007
年代: 1981
DOI:10.1111/j.1423-0410.1981.tb01049.x
出版商: Blackwell Publishing Ltd
数据来源: WILEY
摘要:
AbstractRed cells stored under blood bank conditions normally show less than 1% spontaneous in vitro hemolysis even after 5 weeks; larger hemolysis may be found if the cells are suspended and stored in a saline‐adenine‐glucose (SAG) solution with very little trapped plasma. Delay of the addition of the suspension medium, return of 25 ml plasma after a maximal plasma harvest, addition of mannitol 10–30 mmol.1‐1to the suspension medium were alternative and effective ways of keeping the spontaneous lysis within normal limits. Mechanical traumatization (centrifugation or shaking) caused considerably more damage to the red cells when these were highly concentrated than when they were diluted. A cell suspension in SAG is a more suitable product for hemotherapy than strongly packed red cell conce
点击下载:
PDF
(477KB)
返 回