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The Influence of Magnesium on Visual Field and Peripheral Vasospasm in Glaucoma

 

作者: Ana Zulema Gaspar,   Paul Gasser,   Josef Flammer,  

 

期刊: Ophthalmologica  (Karger Available online 1995)
卷期: Volume 209, issue 1  

页码: 11-13

 

ISSN:0030-3755

 

年代: 1995

 

DOI:10.1159/000310566

 

出版商: S. Karger AG

 

关键词: Calcium channel blockers;Magnesium;Visual fields;Vasospasm;Glaucoma

 

数据来源: Karger

 

摘要:

Previous studies indicated calcium channel blockers to be of some help for normal-tension glaucoma patients. The present study evaluates the effect of magnesium, a ‘physiological calcium blocker’, in 10 glaucoma patients (6 with primary open-angle glaucoma, 4 with normal-tension glaucoma). All patients had a digital cold-induced vasospasm. Magnesium (121.5 mg) was administered twice a day for a month. After 4 weeks of treatment, the visual fields tended to improve. All three video-nailfold-capillaroscopic parameters [blood cell velocity (in mm/ s) before and after cooling, cold-induced blood flow cessation (in seconds) as well as the number of capillaries per microscopic field which showed such a blood flow cessation] as well as digital tempertature improved significantly. Systemic blood pressure and pulse rate remained stable. In conclusion, magnesium improves the peripheral circulation and seems to have a beneficial effect on the visual field in glaucoma patients with vasospasm.

 

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