AbstractThe responsiveness of mothers to their infants has been found to make an important contribution to children's development. Mothers' cognitive ability, emotional state, and life stresses may influence their responsiveness, as may the medical condition of their infants. The patterns of influence may vary between groups of children with different biological risk conditions and should be examined carefully to determine intervention points for different groups.Forty mothers and their 3‐month‐old (corrected age) infants with intraventricular hemorrhage (IVH) were observed in free play. Mothers' depressive symptoms, cognitive skills, and the degree of infants' IVH were assessed and expected to be influences on mothers' responsiveness. Results indicated that mothers' depressive symptoms and cognitive skills were associated with their responsiveness, but that depressive symptoms were the stronger predictor. Post hoc analyses suggested that socioeconomic status and depressive symptoms may have related effects on mothers' behav