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A case of unexplained mild Rh (D) haemolytic diseasein utero

 

作者: I. M. Bromilow,   I. Downing,   S. A. Walkinshaw,   C. R. Welch,   J. K. M. Duguid,  

 

期刊: Transfusion Medicine  （WILEY Available online 1995）
卷期: Volume 5, issue 1  

页码: 31-35

 

ISSN:0958-7578

 

年代: 1995

 

DOI:10.1111/j.1365-3148.1995.tb00182.x

 

出版商: Blackwell Publishing Ltd

 

关键词: anti‐Rh (D);biofunctional assays;fetal blood sampling;haemolytic disease of the newborn

 

数据来源: WILEY

 

摘要:

SUMMARY.This report describes the case of a patient with a history of HDN complicated by fetal losses, in which the alloantibody in this particular pregnancy did not appear to cause HDNin utero.No protective HLA‐DR antibodies could be demonstrated, and transport of IgG across the placenta appeared to be normal. The infant's red cells possessed a normal D antigen and his mononuclear phagocyte system appeared unimpaired. However, the number of molecules of IgG boundin vivoper fetal red cell was below the level usually associated with significant haemolysis and HD

 

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