Changes in lipid profile observed in children over the course of infectious disease
作者:
Ersilia Garbagnati,
期刊:
Acta Pædiatrica
(WILEY Available online 1993)
卷期:
Volume 82,
issue 12
页码: 948-952
ISSN:0803-5253
年代: 1993
DOI:10.1111/j.1651-2227.1993.tb12606.x
出版商: Blackwell Publishing Ltd
关键词: Atherosclerosis;dyslipidemia;infectious illness;stress
数据来源: WILEY
摘要:
Lipid profile was evaluated prospectively in 23 consecutive children, aged 3.2–14.9 years, admitted to the hospital with a febrile illness (pneumonia, upper respiratory tract infection, diarrhea, pyelonephritis, mononucleosis, appendicitis). The degree of dyslipidemia associated with fever was assessed using each child as his/her own control and by comparison with 93 non‐febrile children who had no evidence of fever during the past six months. Total cholesterol decreased during the symptomatic phase of the disease. The magnitude and duration of its decrease appeared to be related to the degree and duration of fever. Low HDL‐cholesterol and hypertriglyceridemia were observed during the late stage of the febrile disease and were still detected in the convalescent phase. This study suggests that in children, transient and sometimes prolonged lipid changes may occur in association with an infectious febrile disease. This effect is important for defining the appropriate timing for screening for dyslipid
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