Conjugated linoleic acid: effects on plasma lipids and cardiovascular function
作者:
Pramod Khosla,
Thomas Fungwe,
期刊:
Current Opinion in Lipidology
(OVID Available online 2001)
卷期:
Volume 12,
issue 1
页码: 31-34
ISSN:0957-9672
年代: 2001
出版商: OVID
数据来源: OVID
摘要:
Conjugated linoleic acid is a collective name for mixtures of several positional and geometric conjugated dienoic isomers of linoleic acid, which have been shown to impact favorably on several biological processes, particularly carcinogenesis. Recent studies have clearly established that thec9,t11 andt10,c12 isomers have distinct biological effects. The latter may be of particular importance in affecting blood lipids. Because conjugated linoleic acid has been suggested to be anti-atherogenic, this review is focused on its effects on cardiovascular function. Careful scrutiny of the literature suggests that at present it is premature to assign any beneficial role to conjugated linoleic acid in terms of its ability to impact either blood lipids or atherogenesis.
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