Prophylactic use of antithrombin III concentrate following surgery in congenital antithrombin III deficiency
作者:
H. HAMBLEY,
J. F. DAVIDSON,
I. D. WALKER,
T. MENZIES,
期刊:
Clinical&Laboratory Haematology
(WILEY Available online 1987)
卷期:
Volume 9,
issue 1
页码: 27-31
ISSN:0141-9854
年代: 1987
DOI:10.1111/j.1365-2257.1987.tb01379.x
出版商: Blackwell Publishing Ltd
关键词: antithrombin III deficiency;antithrombin III concentrate;replacement therapy during surgery;prophylaxis against venous thrombosis
数据来源: WILEY
摘要:
SummaryAntithrombin III is the major physiological inhibitor of thrombin, and congenital deficiency of antithrombin III is associated with increased risk of venous thrombosis either spontaneously or following trauma, surgery or pregnancy. The successful use of antithrombin III concentrate during and following surgery to prevent venous thrombosis is described in a previously asymptomatic man with familial antithrombin III deficiency.
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