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Prophylactic use of antithrombin III concentrate following surgery in congenital antithrombin III deficiency

 

作者: H. HAMBLEY,   J. F. DAVIDSON,   I. D. WALKER,   T. MENZIES,  

 

期刊: Clinical&Laboratory Haematology  (WILEY Available online 1987)
卷期: Volume 9, issue 1  

页码: 27-31

 

ISSN:0141-9854

 

年代: 1987

 

DOI:10.1111/j.1365-2257.1987.tb01379.x

 

出版商: Blackwell Publishing Ltd

 

关键词: antithrombin III deficiency;antithrombin III concentrate;replacement therapy during surgery;prophylaxis against venous thrombosis

 

数据来源: WILEY

 

摘要:

SummaryAntithrombin III is the major physiological inhibitor of thrombin, and congenital deficiency of antithrombin III is associated with increased risk of venous thrombosis either spontaneously or following trauma, surgery or pregnancy. The successful use of antithrombin III concentrate during and following surgery to prevent venous thrombosis is described in a previously asymptomatic man with familial antithrombin III deficiency.

 

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