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HLA and Mycobacterial Infection: Increased Frequency of B8 in Japanese Leprosy*

 

作者: Hajime Takata,   Masaharu Sada,   Shinji Ozawa,   Susumu Sekiguchi,  

 

期刊: Tissue Antigens  （WILEY Available online 1978）
卷期: Volume 11, issue 1  

页码: 61-64

 

ISSN:0001-2815

 

年代: 1978

 

DOI:10.1111/j.1399-0039.1978.tb01225.x

 

出版商: Blackwell Publishing Ltd

 

数据来源: WILEY

 

摘要:

A total of 60 leprosy patients, 28 of lepromatous and 32 of tuberculoid form, and 70 active tuberculosis patients was compared with a control of 184 for 34 HLA specificities. The most interesting finding was an increased frequency (10.0%) for HLA‐B8 (correctedP= 0.062, relative risk = 20.3) in the leprosy patients as compared with the control group, despite the fact that the frequency of HLA‐B8 was extremely low in Japanese. Furthermore, all leprosy patients with B8 had leprous member(s) in their fam

 

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