Erythrocyte Sodium Transport at Twenty‐Year Follow‐Up of Childhood Hypertension
作者:
Makoto Uchiyama,
Teruyuki Ogawa,
Kaoru Sakai,
期刊:
Pediatrics International
(WILEY Available online 1992)
卷期:
Volume 34,
issue 1
页码: 42-45
ISSN:1328-8067
年代: 1992
DOI:10.1111/j.1442-200X.1992.tb00923.x
出版商: Blackwell Publishing Ltd
数据来源: WILEY
摘要:
Twelve‐hour urinary sodium excretion, the number of sodium pump sites (Bmax) and the Na/K flux ratio in erythrocytes were measured in 13 previously diagnosed hypertensive subjects. At the time of the study, six subjects were still hypertensive and showed a significantly lower Na/K flux ratio in erythrocytes than the remaining seven subjects who were normotensive. Bmax was also lower in the hypertensive group compared to the normotensive group, although this was not statistically significant. Urinary Na excretion did not show any significant difference between the two groups. These findings suggest that a cell membrane sodium transport defect may have a role in the development of essential hypertension in adult lif
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