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Isolation of a human laminin B2 (LAMB2) cDNA clone and assignment of the gene to chromosome region 1q25→q31

 

作者: Y. Fukushima,   T. Pikkarainen,   T. Kallunki,   R.L. Eddy,   M.G. Byers,   L.L. Haley,   W.M. Henry,   K. Tryggvason,   T.B. Shows,  

 

期刊: Cytogenetic and Genome Research  （Karger Available online 1988）
卷期: Volume 48, issue 3  

页码: 137-141

 

ISSN:1424-8581

 

年代: 1988

 

DOI:10.1159/000132610

 

出版商: S. Karger AG

 

数据来源: Karger

 

摘要:

Laminin B2 is one of the three polypeptide chains of laminin. a large, complex glycoprotein synthesized by a variety of cells and specifically deposited in basement membranes. A cloned cDNA that encodes the human laminin B2 chain was isolated and characterized. The human laminin B2 gene (LAMB2) was assigned to region 1q25→q31 by (1) hybridization of the probe to DNA from a panel of human × mouse somatic cell hybrids containing different human chromosomes and (2) in situ hybridization to isolated metaphase chromosom

 

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