Transforming Growth Factors in the Regulation of Malignant Cell Growth and Invasion
作者:
KeskiJorma,
PostlethwaiteArnold E.,
MosesHarold L.,
期刊:
Cancer Investigation
(Taylor Available online 1988)
卷期:
Volume 6,
issue 6
页码: 705-724
ISSN:0735-7907
年代: 1988
DOI:10.3109/07357908809078038
出版商: Taylor&Francis
数据来源: Taylor
摘要:
AbstractINTRODUCTIONThe interactions between cells and their extracellular matrices are controlled by various intracellular and exogenous signals. The control of these interactions by polypeptide growth factors appears to involve different levels of regulation. Growth factors can, in addition to the regulation of cell proliferation, direct cell migration and movement, alter the production of different connective tissue components, and regulate extracellular proteolysis. Of particular interest are the autocrine and paracrine growth factors produced by both normal and malignant cells (1-5).
点击下载:
PDF (1875KB)
返 回