Antifibrinolytic Activity in Middle Ear Effusion
作者:
Yukiyoshi Hamaguchi,
Yasuo Sakakura,
Kotaro Ukai,
Masuichi Ohi,
Yasuro Miyoshi,
期刊:
ORL
(Karger Available online 1984)
卷期:
Volume 46,
issue 5
页码: 235-241
ISSN:0301-1569
年代: 1984
DOI:10.1159/000275716
出版商: S. Karger AG
关键词: Middle ear effusion;Secretory otitis media;Plasmin;Plasminogen activator;Streptokinase proactivator.
数据来源: Karger
摘要:
No activity of the plasmin and plasminogen activators could be detected in middle ear effusion (MEE). A streptokinase proactivator, which was not plasminogen and markedly enhanced the activation of plasminogen by streptokinase, could be detected. MEE had an apparent inhibitory activity against both thiol protease (papain) and serine proteases (plasmin and trypsin). All these findings indicate that MEE contains unsaturated protease inhibitors and is in a state of predominance of inhibitors over fibrinolytic activity.
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