Hormonally Enhanced Proliferation of Human Breast Cancer in Organ Culture
作者:
Michael D. Lagios,
期刊:
Oncology
(Karger Available online 1974)
卷期:
Volume 29,
issue 1
页码: 22-33
ISSN:0030-2414
年代: 1974
DOI:10.1159/000224885
出版商: S. Karger AG
关键词: Human breast carcinoma;In vitroorgan explant culture;Hormonally dependent growthin vitro;17β-estradiol;Testosterone;Ovine prolactin
数据来源: Karger
摘要:
A method of short-term organ culture in chemically-defined media of human mammary carcinoma is described. Hormonally dependent proliferation over a 48-hour period is demonstrable in some human breast carcinomas, and uniform maintenance of the explants was obtained over the 48-hour period of incubation. The method permits routine explanting of an individual patient’s carcinoma in the organ culture system described, and may eventually provide useful information for management of advanced breast carcinoma with appropriate antihormonal therap
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