Neurological studies on polychlorinated biphenyl (PCB)‐poisoned patients
作者:
Lie‐Gan Chia,
Fu‐Li Chu,
期刊:
American Journal of Industrial Medicine
(WILEY Available online 1984)
卷期:
Volume 5,
issue 1‐2
页码: 117-126
ISSN:0271-3586
年代: 1984
DOI:10.1002/ajim.4700050110
出版商: Wiley Subscription Services, Inc., A Wiley Company
关键词: PCB poisoning;peripheral neuropathy;nerve conduction velocity (NCV);cerebrospinal fluid (CSF);electroencephalography (EEG);blood or CSF PCB concentration.
数据来源: WILEY
摘要:
AbstractThirty‐five patients out of the 2,000 PCB‐poisoned cases that occurred in central Taiwan in 1978 were neurologically studied in 1980. Neurological manifestation included clinical peripheral sensory neuropathy in about two thirds of the cases, headache in two‐fifths and dizziness in one‐third. There was no relationship between the blood PCB concentration in patients with neurological manifestation and those without. Sensory nerve conduction velocity was reduced in about half of the cases and motor nerve conduction was delayed in about one‐third of the cases, which suggested that PCB poisoning apparently affected not only sensory nerve conduction but also motor nerve conduction. Normal CSF PCB concentrations (0.5–2.3 ppb) indicated that PCB had difficulty penetrating the blood‐brain barrier. A mildly abnormal EEG pattern was found in one fifth of twent
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