153 schizophrenic men from southern Sweden, hospitalized for schizophrenia and born between 1881 and 1900, experienced poor or favorable outcome independently of presence or absence of regressive schizophrenia in their sibs or parents. Homotypy for outcome was not observed within schizophrenic families. Poor prognosis was significantly more common in men with early onset of schizophrenic symptoms than in men with late manifestation of schizophrenia.