Oral Retinoid (Ro 10-9359) in Children with Lamellar Ichthyosis, Epidermolytic Hyperkeratosis and Symmetrical Progressive Erythrokeratoderma
作者:
Lourdes Tamayo,
Ramón Ruiz-Maldonado,
期刊:
Dermatology
(Karger Available online 1980)
卷期:
Volume 161,
issue 5
页码: 305-314
ISSN:1018-8665
年代: 1980
DOI:10.1159/000250382
出版商: S. Karger AG
关键词: Retinoid in children;Lamellar ichthyosis;Epidermolytic hyperkeratosis;Symmetrical progressive erythrokeratoderma
数据来源: Karger
摘要:
8 children with lamellar ichthyosis, 1 with epidermolytic hyperkeratosis and 5 with symmetrical progressive erythrokeratoderma were treated with a new aromatic retinoid (Ro 10-9359). Clinical improvement was dramatic. The children acquired an appearance never obtained before with other managements. The treatment had to be maintained to prevent recurrence. The tolerance to the drug was good. The side-effects were minimal and tended to disappear after several months of treatment. Our results suggest that because of its efficacy, good tolerance and easy administration, the oral retinoid Ro 10-9359 is at present the treatment of choice for the great ichthyotic disorders of children.
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