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Effects of Storage on the Pyruvate‐Lactate System and Random Migration of Human Granulocytes

 

作者: J.L. Paul,   A. El Abbouyi,   M. Roch‐Arveiller,   J. P. Giroud,   J. Agneray,   J. Yonger,   D. Raichvarg,  

 

期刊: Vox Sanguinis  （WILEY Available online 1987）
卷期: Volume 52, issue 1‐2  

页码: 24-26

 

ISSN:0042-9007

 

年代: 1987

 

DOI:10.1111/j.1423-0410.1987.tb02983.x

 

出版商: Blackwell Publishing Ltd

 

数据来源: WILEY

 

摘要:

Abstract.This work demonstrates a time‐dependent loss of polymorphonuclear neutrophilic leukocyte (PMN) functions during the first 48 h with only slight lysis and release of cellular LDH. It confirms that storage decreases ATP levels in PMNs and significantly increases intracellular lactate and pyruvate. These data correlated with an inhibition of PMN migratory function and a considerable decrease in chemiluminescence respons

 

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