Lysosomal Changes and Enterocytic Copper Deposits in Wilson’s Disease
作者:
G. Gasbarrini,
G.R. Corazza,
F. Bonvicini,
期刊:
Digestion
(Karger Available online 1979)
卷期:
Volume 19,
issue 5
页码: 346-348
ISSN:0012-2823
年代: 1979
DOI:10.1159/000198388
出版商: S. Karger AG
数据来源: Karger
摘要:
In 4 siblings, of whom 2 had symptoms of Wilson’s disease, electron microscopy showed that the number and size of lysosomes in the enterocytes were increased compared with controls. Electron-dense aggregates, observed near the lysosomes in the 2 symptomatic patients and 1 other sibling, were shown, by means of a microanalytical method, to contain copper. These findings could suggest a possible role of the small intestine in Wilson’s dise
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