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Osteosarcoma Resembling Osteoblastoma and Its Heterotransplantation into Nude Mice

 

作者: Takayuki Nojima,   Hideo Yamaguchi,   Kazuo Nagashima,   Yuji Nagai,   Makoto Kanda,  

 

期刊: Pathology International  (WILEY Available online 1992)
卷期: Volume 42, issue 1  

页码: 75-81

 

ISSN:1320-5463

 

年代: 1992

 

DOI:10.1111/j.1440-1827.1992.tb01114.x

 

出版商: Blackwell Publishing Ltd

 

关键词: Bone;Osteosarcoma;Osteoblastoma;Nude mouse;Ultrastructure

 

数据来源: WILEY

 

摘要:

We describe a case of bone tumor in the left tenth rib that was diagnosed as a low‐grade osteosarcoma resembling osteoblastoma. This diagnosis was supported by clinical, radiologic, and histologic findings. Specimens of this tumor were transplanted into nude mice, and the morphology of the transplanted tumors was examined. The transplanted tumors were similar histologically to the parent tumor. Ultrastructurally, the transplanted osteoblasts showed irregular, indented nuclei, dilated endoplasmic reticulum, and varying amounts of intercellular junctional complexes. Our transplantable tumor could be valuable as an experimental model for studies on this tumor typ

 

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