SummarySolid phase enzyme immunoassay (EIA) and passive haemagglutination techniques were used to study the occurrence of IgG‐type antibodies against feline and bovine epithelial extracts among RAST‐positive patients, senior veterinary students, cat fanciers (representing exposed subjects) and healthy controls. In most groups both techniques exhibited equal sensitivity being positive in about half of the RAST‐positive cases. The levels of both EIA‐reactive IgG‐class and IgA‐class antibodies were increased in most of the sera (>mean + 2 s.d. of controls), while only a few sera showed increased