Monoclonal Immunoproliferative Disorder of B-Lymphocytes IgD/λChanging from Chronic Lymphocytic Leukaemia to Myeloma and Plasmacytic Leukaemia Pattern
作者:
G. Buchi,
G. Palestro,
E. Leonardo,
G. Termine,
R. Autino,
期刊:
Acta Haematologica
(Karger Available online 1982)
卷期:
Volume 68,
issue 2
页码: 105-108
ISSN:0001-5792
年代: 1982
DOI:10.1159/000206960
出版商: S. Karger AG
关键词: Chronic lymphocytic leukaemia;Derepression in lymphocyte transformation;Myeloma and plasmacytic leukaemia
数据来源: Karger
摘要:
An immunoproliferative disorder with M component lgD/λand a strong decrease of the other Ig classes in the serum is reported. The peculiarity of this disorder consists in the shift from a predominant chronic lymphocytic leukaemic pattern, at the beginning, to a true myeloma with plasmacytic leukaemia IgD/λ several months later. The possibility of the removal, in this case, of the initial precocious block with derepression or ‘switch on’ in transformation of the malignant lymphocyte clone and, consequently, change of a type of malignant lymphoma into another more evoluted and more malignant type is disc
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