EnteropathogenicE. coliGastroenterocolitis in Neonates Treated with Fosfomycin
作者:
C.G. Taylor,
E. Mascarós,
J. Román,
M. Paz,
M. Santos,
A. Muñoz,
M. Gobernado,
期刊:
Chemotherapy
(Karger Available online 1977)
卷期:
Volume 23,
issue 1
页码: 310-314
ISSN:0009-3157
年代: 1977
DOI:10.1159/000222068
出版商: S. Karger AG
关键词: Fosfomycin;EnteropathogenicE. coli;Gastroenterocolitis
数据来源: Karger
摘要:
The effect of calcium salt of fosfomycin in the treatment of 43 neonates suffering from acute gastroenterocolitis produced by enteropathogenic E. coli is evaluated. The minimal inhibitory concentration of these E. coli was, generally, lower that 128 μg/ml. Dosages of 150–200 mg/kg body weight/day were administered orally every 8 h. This treatment lasted for 4 days only. Clinical evolution was favorable in 38 (88%) babies and bacteriological evolution in 30 (70%). In eight cases a different flora to the initial was selected during the treatment with fosfomycin. None of the cases treated showed any toxic alteration attributed to the antibiot
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