Role of Interleukin 8 in the Pathogenesis of Proliferative Vitreoretinopathy
作者:
Ahmet Aksünger,
Meral Or,
Hamza Okur,
Berati Hasanreisoğlu,
Haluk Akbatur,
期刊:
Ophthalmologica
(Karger Available online 1997)
卷期:
Volume 211,
issue 4
页码: 223-225
ISSN:0030-3755
年代: 1997
DOI:10.1159/000310794
出版商: S. Karger AG
关键词: Cytokines;Interleukin 8;Proliferative vitreoretinopathy;Retinal detachment;Vitreos
数据来源: Karger
摘要:
We investigated the role of interleukin 8 (IL-8) in the pathogenesis of proliferative vitreoretinopathy (PVR). The IL-8 level in the vitreous and the blood of 20 patients with PVR was measured by a specific enzyme-linked immunoassay method. Vitreous from cadaver eyes (n = 20) was used as the control. The IL-8 level in the vitreous was between 31.3 and 65 pg/ml in 40% of eyes with PVR. IL-8 was detected neither in the blood of the patients with PVR nor in the vitreous from cadaver eyes. IL-8 levels in the vitreous did not correlate with either the grade of PVR or the duration of symptoms. These results suggest that IL-8 may play a role in the pathogenesis of PVR.
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