Application of High-Speed Countercurrent Chromatography/Electrospray Ionization Mass Spectrometry (HSCCC/ESIMS) in Natural Products Chemistry
作者:
Z. Kong,
K.L. Rinehart,
R.M. Milberg,
W.D. Conway,
期刊:
Journal of Liquid Chromatography & Related Technologies
(Taylor Available online 1998)
卷期:
Volume 21,
issue 1-2
页码: 65-82
ISSN:1082-6076
年代: 1998
DOI:10.1080/10826079808001936
出版商: Taylor & Francis Group
数据来源: Taylor
摘要:
In this paper, we describe the technique of analytical highspeed countercurrent chromatography coupled with electrospray ionization mass spectrometry (HSCCC/ESIMS) for the first time, and evaluate its performance in terms of chromatography and mass spectrometry. This technique demonstrates the capability and resolving power of HSCCC in the separation of a few natural product mixtures and utilizes ESIMS as a detector with continuous detection and high sensitivity. Application of this HSCCC/ESIMS system is illustrated by the separation and detection of biologically important compounds.
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