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In vitrocytotoxicity testing of natural products using guinea‐pig ear keratinocytes

 

作者: Ann Harris,   Alison T. Keene,   J. David Phillipson,   David C. Warhurst,  

 

期刊: Phytotherapy Research  （WILEY Available online 1988）
卷期: Volume 2, issue 1  

页码: 25-29

 

ISSN:0951-418X

 

年代: 1988

 

DOI:10.1002/ptr.2650020103

 

出版商: John Wiley&Sons, Ltd.

 

关键词: Cytotoxicity;in vitrotest;guinea‐pig ear keratinocytes;alkaloids

 

数据来源: WILEY

 

摘要:

AbstractA simple test is described in which the inhibition of uptake of [G‐3H]thymidine into guinea‐pig ear keratinocytesin vitro, has been used as an assessment for cytotoxicity of a series of alkaloids. The alkaloids tested include emetine, colchicine, coronaridine, ajmaline, aricine, vincristine, leurosine, quinamine, 3‐epiquinamine, quinine, quinidinone, cichonidine, berberine and atr

 

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