摘要:

The antibody response in four groups of five rabbits, three vaccinated with BCG and one with the vole bacillus, was measured by the hemagglutination reaction. In the control series, in which the standard BCG vaccination procedure was carried out, a mean titer of 1:16 or higher appeared on the third week and was maintained for eight weeks. In the second series, in which the vaccine was administered in two doses, with a three-week interval, a titer of 1:16 or higher appeared on the fourth week and was maintained for 11 weeks. In the third series the vaccine was prepared in a water-in-oil emulsion and administered as in the control series. A titer of 1:16 or higher appeared on the second week and was maintained for 13 weeks. In the fourth series the standard procedure was followed, except that the vole bacillus was substituted for BCG. A titer of 1:16 appeared on the fifth week and was maintained for three weeks. The differences between the results in series three and in series four and those of the control were significant, whereas the results in series two did not differ significantly from those of the control.

ISSN:0008-4166    

DOI:10.1139/m55-011

出版商:NRC Research Press    

年代:1954

数据来源: NRC