摘要:
IntroductionSuccessful crystal engineering of organic materials1requires access to a large number of synthons and a detailed understanding of the subtle interplay of relatively weak interactions which can become important in the solid state. Desiraju and others2have described a wide variety of intermolecular contacts which can be used to control the architecture of organic solids. Despite the considerable interest in the use of 2,6disubstituted pyridines in the organisation of molecular architecture,3the Cambridge Structural Database4contains only one example of a free pyridine ring bearing an ester functionality at both C2 and C6,5and even in that case all other positions about the pyridine ring are also substituted. All other ‘hits’ incorporating the 2,6dicarboxylato unit are either concerned with situationsin which the pyridine ring is part of a macrocyclic skeleton, or cases where strong electrostatic interactions dominate,e.g.in metalion complexes6or in the parent diacid and its salts.4,7We now report preliminary results of a study of the solidstate behaviour of a number of simple pyridine-2,6dicarboxylate esters1a–fand a 3,5disubstituted analogue2.
ISSN:1466-8033
DOI:10.1039/b107221h
出版商:RSC
年代:2001
数据来源: RSC