摘要:

A critical description of the antimony trichloride method for the determination of vitamin A is presented. Low values for vitamin A result from:(1) Incomplete extraction from the alcoholic soap solution by using petroleum ether instead of ethyl ether,(2) Incomplete separation of the layers during extraction and washing,(3) Incomplete filtration through anhydrous sodium sulphate.If strict attention is paid to details of procedure, the method gives consistent and reproducible results. Uncertainty in regard to the exact factor for converting theEvalues to international units makes it impossible at this time to state accurately the absolute values. It is pointed out that this in no way detracts from the usefulness of the chemical test.

ISSN:1923-4287    

DOI:10.1139/cjr44b-004

出版商:NRC Research Press    

年代:1944

数据来源: NRC

摘要:

1,1-Diphenylindan was treated with one molecule of bromine. It yielded a monobromide, which was condensed with methyl and ethyl alcohols, piperidine,p-toluidine, and aniline. With aqueous solutions of potassium carbonate, the monobromide directly gave rise to 1,1-diphenylindene and small quantities of diphenylindanyl ether.The condensation of the monobromide with sodium ethyl malonate yielded ethyl 1,1-diphenyl-3-indanmalonate from which 1,1-diphenyl-3-indanmalonic and 1-1-diphenyl-3-indanacetic acids were prepared. A few derivatives of these acids were also obtained.To establish the constitution of 1,1-diphenyl-3-indanacetic acid and, hence, that of the monobromide and of the other compounds, this acid was prepared directly from 3,3-diphenyl-1-indanone by a Reformatsky reaction with ethyl bromoacetate.The method of preparation of 1,1-diphenylindan has been improved, 1,1-diphenylindene has been obtained by new methods, and the following compounds are described, as far as the authors are aware, for the first time: 3-bromo-1,1-diphenylindan, 3-methoxy-1,1-diphenylindan, 3-ethoxy-1,1-diphenylindan, 3-N-piperidyl-1,1-diphenylindan, N-phenyl-1,1-diphenyl-3-indanamine, N-p-tolyl-1,1-diphenyl-3-indanamine, ethyl 1,1-diphenyl-3-indanmalonate, 1,1-diphenyl-3-indanmalonic acid, 1,1-diphenyl-3-indanmalonic acidp-nitrobenzyl ester, silver salt of 1,1-diphenyl-3-indanmalonic acid, 1,1-diphenyl-3-indanacetic acid, 1,1-diphenyl-3-indanacetic acidp-nitrobenzyl ester, silver salt of 1,1-diphenyl-3-indanacetic acid, 1,1-diphenyl-3-indanacetanilide, 1,1-diphenyl-3-indanacetamide, 1,1-diphenyl-3-indanacetonitrile, 1,1-diphenyl-3-indanethylamine hydrochloride, ethyl 3-hydroxy-1,1-diphenyl-3-indanacetate, ethyl 1,1-diphenyl-3-indeneacetate, 1,1-diphenyl-3-indeneacetic acid, silver salt of 1,1-diphenyl-3-indeneacetic acid, 1,1-diphenyl-3-indeneacetic acidp-nitrobenzyl ester, ethyl 1,1-diphenyl-3-indanacetate.

ISSN:1923-4287    

DOI:10.1139/cjr44b-005

出版商:NRC Research Press    

年代:1944

数据来源: NRC

摘要:

4-Camphorylthiosemicarbazide has been prepared by the action of hydrazine hydrate on camphorylthiocarbimide. The analogous semicarbazide has been prepared by a similar reaction. Neither of these substances displays the gel-forming characteristics of 4-camphoryl-2-phenylthiosemicarbazide. From these substances a number of thiosemicarbazones and semicarbazones have been prepared, but although camphoryl-thiosemicarbazide and -semicarbazide are optically active they do not seem to be useful substances for the resolution of racemic aldehydes or ketones. A number of 4-camphoryl-1-(or 2)-arylthiosemicarbazides have been prepared but none displayed the colloidal nature of the 2-phenyl-compound.

ISSN:1923-4287    

DOI:10.1139/cjr44b-006

出版商:NRC Research Press    

年代:1944

数据来源: NRC