摘要:

The theory of multiple allelic genes accounting for the inheritance of theRhreactions is well established. Fisher's hypothesis of eight genes, six pairs of allelic antigens, and six specific antibodies is the most comprehensive offered.The blood of 606 Canadians of Japanese race was tested with the four available antisera. Since this sample included entire families, gene analysis was based on a subsample of 217 unrelated individuals. The resulting analysis, based on Fisher's hypothesis, is given, and the probable reason for a discrepancy in the findings presented and further tested. Estimates of gene frequencies in per cent were as follows:These results are compared with previous studies on Japanese, and examined in relation to Fisher's hypothesis of three linked loci, and Fisher and Race's hypothesis of crossing over of elementary antigens.

ISSN:1923-4287    

DOI:10.1139/cjr46e-014

出版商:NRC Research Press    

年代:1946

数据来源: NRC

摘要:

The blood of 129 parents and 182 children was tested by the four anti-Rhsera, anti-D, anti-C, anti-E, and anti-c(or anti-Rho, -Rh′, -Rh″, and -Hr′). The data obtained were in agreement with R. A. Fisher's hypothesis of the allelicRhgenes. No exceptions to expected results were found.

ISSN:1923-4287    

DOI:10.1139/cjr46e-015

出版商:NRC Research Press    

年代:1946

数据来源: NRC